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Saturday, October 5, 2019

English Intensive Writing Essay Example | Topics and Well Written Essays - 1750 words

English Intensive Writing - Essay Example The game Call of Duty seems to be an FPS game that includes a lot of violence with a background of World War II, but it is really about the portrayal of justice and how the United States thinks that they are a righteous power. The task of visualizing World War II has recently been taken up by new media, particularly video games, which include Call of Duty. This has therefore created new social and political perspectives of the war other than what movies like Pearl Harbor or Saving Private Ryan would naturally point out to. World War II games features military combat. Nevertheless, more than this, the World War II game has somehow become a â€Å"resilient formula and an important way that the cultural memory of the war was activated for a growing segment of the population† (Allison 183). Thus, such games have somehow illustrated a justified military force where the United States acted as the savior of the world. One more quality of Call of Duty and other World War II shooter games is the fact that the player can take the role of â€Å"an American paratrooper, a British Special Forces operative, and a Russian tank commander,† thus adding an element of equality to the game, or the idea that other countries, like Great Britain and Russia, believed in America’s cause during World War II (â€Å"Exclusive First Look†). The fact that one can play more than just being an American soldier in Call of Duty somehow instills in the minds of those exposed to the game that other countries have consented to the war that America has fought long and hard. The cooperation of other countries especially powerful countries like Great Britain and Russia somehow lends to the idea that America indeed fought a worthwhile war and was therefore justified in its mission of bringing justice to the world. This makes Call of Duty similarly worthwhile, and this makes this particular shooter game highly instrumental in instilling in everyone who plays it the idea that America was the

Friday, October 4, 2019

Romeo and Juliet Essay Example for Free

Romeo and Juliet Essay Yesterday evening, terror had struck the streets of Verona when there was a brawl between the Capulets and the Montagues. The end result was two fatalities and one missing person. Tybalt Capulet, nephew of the Lord Capulet’s wife, was allegedly slain by Romeo Montague, son of the great Lord Montague. Mercutio, kin to Prince Escalus, was the other casualty. He was allegedly slain by Tybalt, using Romeo as a shield when trying to break them up. Benvolio, of the Montagues, was an eye-witness to the terrible scene and was interviewed for hid full report on what happened. According to him, Tybalt wanted to fight Romeo, but Romeo declined and tried to mediate the situation also making alleged suggestions that they were related. And Mercutio, who had some violent tendencies, decided that he would fight Tybalt himself. But, in Romeo’s attempt to solve the problem, he got in between the two of them and Tybalt ended up stabbing Mercutio. He died on the spot. Then, Romeo’s anger got the best of him and he killed Tybalt for killing his best friend. Then, he just decided to flee the scene so he wouldn’t get caught. However, Lady Montague had her own side of the story she said â€Å"Benvolio is a Montague; he is not telling the truth. There must have been twenty guys fighting against Tybalt. Romeo must not live! † Lord Montague had said during his interview, â€Å"Romeo and Mercutio were best friends, he was doing what the law would have done to Tybalt, and he killed him. † A few weeks ago, the Prince declared that if he heard of one more fight between the two infamous families, there would be a death sentence. You would think that with this warning, the families would consider changing their violent ways. We got a few comments from the Prince, saying that the families will pay for the unfortunate events of the terrible night and an immediate exile against Romeo was declared. He clearly stated â€Å"If those who kill are given mercy, that’s as much as giving permission for murder. † As for now, our deepest sympathies go out to the kin of the fatalities.

Thursday, October 3, 2019

Antidepressant Drugs: Types, Effects and Developments

Antidepressant Drugs: Types, Effects and Developments Introduction: Depression is one of the parts of mental disorder which is affecting millions of people worldwide. [6] The logical analytical approach used in clinical and forensic toxicology for the identification of one or more Antidepressant Drugs as a cause of intoxication is largely based on both simple and fast screening methods which cover their extraction and identification including detection of their possible metabolites is been tried to reviewed. Antidepressant: Types Functions Antidepressant drugs cover many varieties of drugs having different modes of actions like [16] etc. Adverse effects Antidepressants are supposed to increase the risk of suicidal thinking and behavior in children accompanying other disorders like depressive and psychiatric disorders. [17] [18] [19] The European Medicines Agency showed warning on the use of Antidepressants which might be increased the risk of suicidal behavior in children and adolescents. [31] TCAs and MAOIs can produce similar kind of side effects like Tachycardia, blurred vision, urinary retention, cardiovascular effects , hypotension, respiratory depression, coma etc. [4] Thus, these drugs may be responsible for the fatality and intoxication and can produce severe effects. Also their growing rate all over the world may show threatening effects which is the matter of global concern. Thus, its increasing prescription rate and adverse effects resulting in a growing interest for determination methods in the Clinical and Forensic field. Biological Samples use for the Screening of Antidepressant Drugs Biological samples are the basic requirement of Forensic and Clinical Toxicology as it solve several related questions which make basis of judgement, consultation and expertise for the above two fields. The matrices generally encountered for analysis are urine [34], hair, nails, vitrous humour etc. The most important biosample used for analytical purposes is Blood. It is a liquid connective tissue of the body composed of different kinds of blood cells suspended in a fluid called plasma. Blood (plasma, serum) is one of the best choices for quantitative and qualitative measurements of drugs of interest because pharmacological or toxicological effects correlate more effectively with their concentrations in blood. [42] Another important biological sample is Urine which is a widely used specimen employed for screening, identification and testing of unknown drugs, forms in high amount, readily available, easy to collect and contains much useful information about the major metabolic functions of the body. [43] Taking Forensic concept in postmortem cases if the positive finding of drug occurs in urine shows that the detected substance or its parent compound might be present in the body some time before death [48] A next alternative to the blood and urine specimen found is Oral fluid for their applications in therapeutic and toxicological drug monitoring [54] When analytical studies get concern with long duration of exposure to the detection window Hair could be as a best biological matrix for the identification and analysis of drugs. It is supposed that drugs or chemicals enter in to hair by passive diffusion from blood capillaries into growing cells and the mechanisms of substance incorporation, analytical methods, result interpretation and practical applications of hair analysis has been well reviewed showing practical utility of hair analysis. [62] Except from all the above given matrices one very precise and rarely encountered biological sample is Vitreous Humor. Its a fluid found between the lens and retina of the eye proved to be the best choice for analytical examinations as it is relatively well isolated and protected from putrefaction. Two different fatality cases were reported where the extraction of drugs is done from Vitreous humor. One case has been reported of citalopram fatality where the extraction of drug is done from Vitreous humor yeilding concentration of citalopram (SSRI) less than 0.04mg/L and in second case venlafaxine fatality is reported where postmortem analysis revealed the concentrations of Fluoxetine (SSRI) and its metabolite Norfluoxetine as 5.2 mg/l and 2.2mg/l respectively. [64] Other than these specimens, body tissues like liver [71], cerebrospinal fluid etc. canalso encounter for toxic and therapeutic drug monitoring biological matrices. Techniques for Sample Preparation Several methods have been published for the determination of one or more antidepressants in biological fluids for therapeutic monitoring or for toxicological purposes. For making biological samples suitable for analytical purposes some treatments should be given to overcome the matrix effects such that the other materials should not interfere with the analytical separation that is the extractability of the analytes in the sample inturn the results of the analysis. [96] These kinds of techniques are rapidly gaining acceptance in bioanalytical applications to reduce both time and labor required to produce bioanalytical results. Thus we can say that these methods give a high selectivity and sensitivity over a wide dynamic range and contribute in formulating very fine detection techniques. Some Commonly Prescribed New Generation Antidepressant Drugs and their Metabolites Several new antidepressants that inhibit the Serotonin (SERT) and Norepinephrine transporters (NET) have been consistently use for therapeutic purposes. [108] are showing below. Sertraline is an effective and highly utilized SSRIs group of drug and â€Å"its principle metabolite is desmethylsertraline.† [41] Another SSRIs group of Antidepressant drug, Fluoxetine has been used worldwide in the therapy of major depression. (3) â€Å"It is primarily metabolized via N-demethylation by the [117] Citalopram is a selective and potent serotonin reuptake inhibitor. [78] Another very important group of Antidepressant drug is SNRIs which includes drugs like Venlafaxine which inhibits serotonin, noradrenaline, and to a lesser extent dopamine reuptake. [39] In the majority of published analytical methods for determination of Antidepressant drugs, gas chromatography and high-performance liquid chromatography, in combination to different kinds of colums operating under different separation conditions, mobile phases and detectors has been used. These were tried to review in the table given below. With high-performance liquid chromatography the analysis is done by using different kinds of detectors like Fluorescence detector, UV detector, Mass detectors etc. For ex. a high-performance liquid chromatographic method is described for the determination of serotonin and norepinephrine reuptake inhibitor (SNRI) in human plasma where Fluorescence detector was used. [140] A survey of most recent multiresidue analytical methods developed for the determination of different kinds of Antidepressant drugs in different types of biological test matrices with their specific cleanup procedures including the choice of mobile phase, stationary phase, detector system and validation data is summarized in the tabular form below. TABLE Abbreviations:APCI atmospheric pressure chemical ionisation, ESI eletrospray ionisation, LLE liquid-liquid extraction, LOD limitation of detection, LOQ limit of quantification, SIM single ion monitoring, SPE solid-phase extraction, SRM selected reaction monitoring , ESI electron spray ionization, UV ultraviolet, FD fluorescence detector, LC_TMS liquid chromatography tandom mass spectrometry, LC_MS, GC_MS gas chromatography mass spectrometry, RP-HPLC reverse phase high performance liquid chromatography. Thus, this table is framed for the comparative study of the major analytical approaches used in the detection and identification of Antidepressant Drugs and their metabolites in different biological matrices in order to develop the new methods with the aim to increase the sample throughput and to improve the quality of analytical methods. Thus, analytical methods for the detection of ADs and their metabolites in biological matrices are of interest in the field of forensic toxicology which involves the analysis of drugs and poisons in biological specimens and interpretation of the results to be applied in a court of law. Several analytical methods have been developed for analysis of these antidepressants in biological matrices. These methods provide a good precision and accuracy over the entire analytical range and allowing the development of very rapid and efficient analytical methods by using newer kind of analytical techniques. Conclusion: As the subject of Antidepressants toxicity is evolving, newer methods for their analysis are also evolving. However, some classes of Antidepressants drugs are less toxic and well tolerated but can lead to Toxic or Fatal Drug interaction. The research in this field is very active and results in a large number of papers published every year. Therefore they may be encountered in many Clinical and Forensic cases. Therefore, this review is mainly aimed to target latest analytical and instrumental methods used for detection and characterization of Antidepressant drugs and their metabolites in biological test matrices in turn focus on their toxic as well as therapeutic aspects which would be definitely prove to be helpful in future research and still there is lots of work required in this area as its prescription rate and toxicity is evolving day by day all over the world and by using non-destructive and sophisticated newer instrumental techniques we can also built a new strategy of examina tion and investigation for the drugs of interest. However, in this study, a decision about whether a studys findings are positive or negative cannot always be based strictly on the primary outcome measure. Future trials should also consider, using different kinds of detecting techniques and methods which would allow for easier comparison and interpretation of results across studies as the subject is of global concern and despite the success of such methods there is a continuing need for sustained innovations. Thus, future work in this area will definitely prove to be a promising from both clinical as well as from forensic prospect.

Wednesday, October 2, 2019

The Age of The Renaissance :: The Renaissance

The Middle Ages is considered by many historians a time period of ignorance, where little or no advancements took place. The church was the center of attention, and instead of a philosophical view of the world, beliefs were centered around superstitions. On the other hand, the rebirth of education and advancements that followed the Middle Ages and was labeled as the Renaissance. There have been arguments as to whether the Renaissance is actually a separate time period, or instead, just a high point of the Middle Ages. The Renaissance was definitely a distinct era. Inspiration from the ancient Greek and Roman people led to humanism beliefs and encouraged man to become multi-talented. Therefore, the Renaissance man, a man who excelled in many areas, became prominent. Also, the ideals of the people changed, and religion no longer ruled their lives. Advancements in all aspects of life virtually improved. Thus, many aspects lead to the change from the Middle Ages to the Renaissance, a ti me period that was undoubtedly distinct from the Middle Ages. During the Renaissance, ideas and beliefs changed greatly. Humanism, a crucial movement to the Renaissance, stressed secular ideas and beliefs and the importance of advocating human’s ideas and values. The movement drew inspiration from the ancient Greek and Roman people. Therefore, classical education began to circulate once again (document 1). The people of the Middle Ages had great amounts of ignorance and believed in faith and false ideas while focusing on childish possessions, but during the Renaissance these ignorant beliefs disappeared and humanism took its place (document 2). The church was no longer the center of life for many and some lost interest in the traditional beliefs that the church was preaching. Yet, it was still an important aspect. The church had lost large amounts of power and wealth due to the humanism movement because people became less reliable on the church and could think and follow ideals on their own. But, the church was rapidly changing during this time period also, because religion was focused on wealth and the money it could obtain (document 5). Instead, many supported the idea that the people who held secular beliefs should be ruled by noblemen that were scholarly, highly educated, and not only concerned with goods (document 5). Entirely new ideas and beliefs began to circulate during the Renaissance, and the church lost much of its great influence.

The Myth of the Lost Cause :: American America History

The Myth of the Lost Cause Following the defeat of the Confederacy and to lift the morale of a shattered people momentum gathered to enshrine the Myth of the Lost Cause which would transform the Southern soldier living and dead, into a veritable hero. In order to come to terms with defeat and a look of failure in the eyes of God, Southerners mentally transformed their memories of the antebellum South. It became a superior civilization of great purity which had been cruelly brought down by the materialistic Yankees. At the head of this revival was the memory of Stonewall Jackson, closely followed by Robert E. Lee (who would rise to the prominent position following his death in 1870). Other generals of the Confederacy who had died during the war followed, as did those who would pass on later. D.H. Hill, a friend of Longstreet published LAND WE LOVE, a magazine devoted to Literature, Military History and Agriculture. In 1869 Hill sold out to a Baltimore periodical, NEW ECLECTIC, which in the same year became the SOUTHERN MAGAZINE, official organ of the SOUTHERN HISTORICAL ASSOCIATION. In 1871 it changed its name to the SOUTHERN MAGAZINE and together with a later periodical, SOUTHERN BIVOUAC kept the memory of the War alive and fresh in the public mind. Filled with poems and stories of loyalty to the LOST CAUSE sent in by veterans. Hill was Stonewall Jackson's brother in law and he filled the magazine with stories, anecdotes and poems of the now legendary general. Other Confederate heroes received their share of attention from a flood of material supplied by readers commemorating Southern dead and using religion to explain the defeat. Book - writing was prolific in the '70s & '80s mainly from veterans but much on the romanticism of the Cause from women. The most prominent of the writer of the period was John Esten Cooke, who was related by birth and marriage to virtually all the prominent families of Virginia he helped enshrine the Confederate dead into chivalric knights and symbols of the LOST CAUSE. Cooke's impressive literary output polarized Southern perceptions of the War transforming the stigma of defeat into a badge of honour that Confederate veterans could wear proudly. His portrayal of the War as a wonderful adventure, in which participation was an honour. When Lee died on 12 Oct. 1870 he was one of a significant number of Confederate heroes running second to Jackson.

Tuesday, October 1, 2019

Changes in School Essay

Education has changed throughout time and will continue changing. With many changes for better or for worse, education will still be a priority for our children. After interviewing two teachers that have been in the education workforce for over twenty years, I realized how much change in society has affected the way teachers taught their students. The first teacher I interviewed had been teaching for twenty-five years and is a sixth grade teacher. She noted that any change in our culture has made a difference in her classroom. As part of the changes the role of schools and education will also be different both in the educational system and in the society. Together with them the role of teachers will also change. The way students are learning is changing therefore, the tools to accommodate these demands are changing as well. She commented that technology is now a great part of today’s education. She said its like an â€Å"explosion of technology† has hit our generation. Although she says that technology has brought many opportunities it has brought challenges as well. For example, it is an advantage for her to integrate computers in her classroom for learning. But it is a huge distraction when her students have cell phones and music player devices in class. She commented that â€Å"children in sixth grade shouldn’t even own cell phones. † They are too young to have cell phones and notices that twenty years ago, her students were not known to have such things. Technology is becoming more and more advanced everyday. Items that are faster and sleeker are replacing items that were once used. The teacher also commented that the role of parents throughout her time in teaching has changed as well. She noticed a change in the amount of parent involvement. She said that parents today are more involved in their child’s education than back then. The second teacher I interviewed, has been teaching for twenty years and is a third grade teacher. She says that the role of teachers in student achievement is critical. Children are not the only ones who must be prepared for change. Teachers must be knowledgeable with any and all changes that occur in our society as well. There have been great educational changes over the past years. There is one role in education that has been forced to keep up with changes brought about by the information age, computers and the changes in society. Before teachers, were the main source of learning and now there are many resources for students to search for answers to their questions. She also says that the number of students and teachers have grown through out her years. During her teaching years she says that parental involvement has generally increased during the last twenty years. And it’s a great factor that has evolved in children’s education. There are also more children with more than one nationality compared to children back then. Yet the world in which our children grow up and go to school has changed immensely. Back then personal computers were expensive, slow and rare. Today, those huge desktops are nearly gone. There were no web browsers and Internet Explorer came later, as did social media, like Google, Facebook and smart phones. We’ve hardly had time to figure out how this explosion of technology affects the way children think and relate to each other. I believe the need of a generation of teachers who aim to develop learners instead of teaching them, who help their students to become independent, who provide students with motivation and interest for life-long learning, is essential in the education of the future. Children today are growing up in a world that has changed significantly over the past twenty years. They are comfortable around technology that they have known all their lives. The changes going on today create an opportunity and a necessity for a transformation in the education system and in the way children are taught. Children must be prepared for a future of continued rapid change.

Monday, September 30, 2019

Dangerous Technology

English 1010 5 October 2012 Dangerous Technology Many people have one. Some have more than one. Odds are pretty good that yours is within reaching distance right now. â€Å"What is it? †, you may ask. The answer is simple: the almighty cell phone. Although cell phones allow easy and quick communication, they are starting to create problems in today’s society: they distract drivers, they interrupt social interaction, and society is unaware of any long term medical issues they could create. One of the most dangerous issues with cell phones is people using them while driving. A distracted driver is a dangerous driver.If someone is reading or sending a text, or even talking on the phone, they are not paying full attention to the road, making it hazardous for themselves and those around them. It has become enough of an issue that many states have passed laws that make using a cell phone while operating a motor vehicle illegal. It is a severe issue with inexperienced drivers, who need as few distractions as possible. Many schools are even stepping up and asking students to pledge not to use their cell phones while driving. Although they are an amazing piece of technology, they are beginning to create social barriers in today’s society.They allow us to always be connected to one another, which is creating a social dependency on being connected. Cell phones are replacing face to face communication. There’s no need to make time in our schedules for people we consider important because they are just a text message away. Many people can’t go without their phones for fear of missing out. It’s like an unspoken anxiety problem. Because of this dependency, cell phones are becoming distractions in social settings. So much that even movie theatres ask their guest to please silence or turn off their cell phones for the presentation.There are some who can’t even be without them to watch a ninety minute movie, for which they paid a pretty penny to see. Just as there are some who can’t make it through dinner with friends without making a call, checking their messages, or even utilizing them for social media sites. At the first hint of boredom in a social setting, people turn to their phones to find a source of entertainment. We’re becoming a society addicted to technology. Cell phones are a fairly new technology really. We do not know if there are long-term, adverse effects of carrying around something that receives and emits satellite signals.They are electronic devices, meaning they emit electricity. Electronic devices are known to produce electromagnetic radiation, something often linked to cancer and tumors. Granted, currently there is no proof directly linking cell phones to cancer. This is just one of issues with cell phones we should be weary of. It’s a potential wolf in sheep’s skin, if you will. Cell phones are seemingly harmless, but who is to say that in another twenty yea rs or so there won’t be widespread cases of cancers all linked to consistent, direct contact of electromagnetic radiation.In conclusion, cell phones are an amazing piece of technology that need to be used more cautiously. Countless vehicle accidents occur every year due to a driver who was distracted by his or her cell phone. Society should learn to make more time for interpersonal relationships, instead of depending on a piece of technology to communicate. Lastly, we should be weary of the effects that could come from carrying around electromagnetic radiation for extended periods of time.